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Wellspring IVF & Women's Hospital • Ahmedabad

Fresh IVF Cycle & Embryo Transfer in Ahmedabad

"The Classic, Continuous Path to Pregnancy."
✓ Medically reviewed by Dr. Pranay Shah, MS (ObGy)

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    Fresh IVF Cycle in Ahmedabad — Stimulation, Retrieval, Transfer in One Continuous Journey

    There is a growing tendency in IVF to default every patient to a freeze-all strategy — freeze all embryos, transfer in a later cycle. It is not wrong. In specific clinical situations — high responders, elevated progesterone, PGT-A planned — it is clearly the better choice. But it is not the universal answer, and applying it universally does not serve every patient.

    Fresh IVF Cycle — The Right Choice for the Right Patient

    Not every patient needs to freeze all embryos and wait an extra 6–8 weeks. For the optimal fresh candidate, this path is faster, equally effective, and more cost-efficient.

    What Is a Fresh Cycle

    An IVF cycle in which the embryo is transferred back to the uterus in the same stimulation cycle it was created — no freezing required.

    Total Duration

    Approximately 3–4 weeks from Day 1 of stimulation to embryo transfer. Pregnancy test 14 days after transfer.

    Best Candidate

    Women under 38 with normal ovarian reserve, normal progesterone on trigger day, 2–5 embryos only, no OHSS risk, no PGT-A planned.

    Transfer Day

    Day 3 (cleavage) or Day 5 (blastocyst) — Dr. Shah’s default is Day 5 blastocyst where embryo number permits.

    Stimulation Protocols — How Dr. Shah Personalises Your IVF

    GnRH Antagonist Protocol

    Best For: Most patients — first-line choice for normal and high responders. PCOS patients.

    Stimulation Duration: Day 2–12.

    Trigger Type: hCG trigger or GnRH agonist trigger.

    Long GnRH Agonist Protocol

    Best For: Endometriosis, adenomyosis, fibroids.

    Stimulation Duration: Down-regulation 14–21 days.

    Trigger Type: hCG trigger.

    Short / Flare Protocol

    Best For: Poor ovarian reserve, low AMH.

    Stimulation Duration: 9–12 days total.

    Trigger Type: hCG trigger.

    Mini-IVF / Minimal Stimulation

    Best For: Very low AMH, poor responders.

    Stimulation Duration: 5–8 days only.

    Trigger Type: hCG trigger or natural LH surge monitoring.

    Understanding IMSI Treatment

    Learn from our experts and get inspired by real patient journeys

    Fresh vs. Frozen Embryo Transfer: Which Has Higher Success?
    Fresh vs. Frozen Embryo Transfer: Which Has Higher Success?
    Fresh vs. Frozen Embryo Transfer: Which Has Higher Success?
    Fresh vs. Frozen Embryo Transfer: Which Has Higher Success?
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    What Actually Happens During Laparoscopy - Step by Step

    The word “surgery” understandably causes anxiety. Understanding exactly what happens – in plain language – transforms this from something frightening to something logical and manageable. Here is every step of a diagnostic and operative laparoscopy at Wellspring IVF:

    Days 1–2

    Pre-Cycle Baseline Assessment

    • Transvaginal ultrasound: antral follicle count (AFC)
    • Blood tests: Day 2 FSH, LH, Estradiol (E2)
    • Protocol confirmed: medication type, starting dose, injection schedule
    • Nurse appointment: injection technique training
    Days 2–3

    First FSH/HMG Injection — Stimulation Starts

    • Gonadotropin injections begin
    • Subcutaneous injection — abdomen or thigh
    • Continue daily until trigger night
    Days 5–6

    First Monitoring Scan + Antagonist Added

    • Transvaginal scan and follicle measurement
    • Estradiol blood test
    • GnRH antagonist starts
    • Dose adjustment by Dr. Shah if needed
    Day 10–12

    Trigger Injection — Final Egg Maturation

    • Trigger decision made once follicles mature
    • Progesterone checked before fresh transfer approval
    • hCG or GnRH agonist trigger selected
    Day 12–14

    Egg Retrieval — Ovum Pick-Up (OPU)

    • Performed under intravenous sedation
    • Transvaginal ultrasound-guided follicle aspiration
    • Recovery: 2–3 hours in the clinic
    Day 14

    ICSI — Sperm Injection & Fertilisation

    • Partner’s semen sample processed
    • ICSI performed on mature eggs
    • Fertilisation report shared next morning
    Days 15–19

    Embryo Development — Day 1 to Day 5

    • Embryos cultured in precision incubators
    • Blastocyst grading performed
    • Surplus embryos vitrified for future FET cycles
    Day 19–20

    Embryo Transfer — The Final Step

    • Best-quality embryo selected for transfer
    • Soft catheter under ultrasound guidance
    • Luteal support begins after transfer
    Day 34

    Beta-hCG Blood Test — Pregnancy Confirmation

    • Serum beta-hCG measured 14 days after transfer
    • Positive: progesterone support continued
    • Negative: cycle review and next-step planning

    Fresh vs Frozen Embryo Transfer — The Objective Comparison

    Factor Fresh Transfer Frozen (FET)
    Total cycle time 3–4 weeks stimulation to result 6–10 weeks
    Endometrium quality May be suboptimal Fully prepared in a dedicated cycle
    OHSS risk Present in high responders Zero
    Cost Lower overall cost Higher due to vitrification and FET
    PGT-A compatible No Yes

    The Evidence on Fresh vs Frozen Success Rates

    Multiple large RCTs show: in normal responders with normal progesterone, fresh transfer success rates are equivalent to FET. In high responders, freeze-all strategies show significantly higher live birth rates due to the OHSS-free, fully prepared endometrium.

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    Day 3 vs Day 5 Transfer — Cleavage vs Blastocyst

    Day 5 Blastocyst Transfer — Dr. Shah’s Preferred Default

    Culturing to blastocyst (Day 5) allows natural selection — embryos with poor developmental potential arrest before reaching blastocyst, eliminating them from the transfer pool without invasive testing.

    When Day 3 Transfer Is Indicated

    Fewer than 3 fertilised embryos, previous blastocyst arrest, or patient age with very few eggs.

    Medications in a Fresh IVF Cycle

    For fertility patients, the choice between laparoscopic and open surgery is not simply a preference – it has direct consequences for recovery speed, adhesion formation, and how quickly you can attempt conception or IVF. Here is the complete comparison:

    Medication Type When Purpose
    Gonal-F / Puregon / Menopur Recombinant FSH or FSH+LH Days 2–12 Stimulates ovarian follicles
    Cetrotide / Orgalutran GnRH Antagonist Days 5–6 until trigger Prevents premature LH surge
    Ovitrelle Trigger injection 34–36h before OPU Final maturation of eggs
    Crinone gel / Utrogestan Progesterone From day after OPU Supports uterine lining

     

    Talk to Dr. Shah About Cavity Optimisation

    Dr. Pranay Shah can advise whether hysteroscopy is likely to change your implantation chances or whether another evaluation pathway is more appropriate first.

    Frequently Asked Questions

    Common questions on fresh transfer candidacy, injections, timing, and fresh versus frozen decisions.
    Ask a Question

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    Begin Your Fresh IVF Cycle at Wellspring IVF, Ahmedabad

    Stimulation → Retrieval → Fertilisation → Transfer — one unbroken journey, 3–4 weeks.
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    Wellspring IVF & Women's Hospital
    Ahmedabad, Gujarat